STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMT5BLysine methyltransferase 5B. (880 aa)    
Predicted Functional Partners:
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.677
LOC100465110
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.617
KMT5A
Lysine methyltransferase 5A.
      
 0.513
ASH1L
ASH1 like histone lysine methyltransferase.
   
  
 0.480
ENSAMEP00000020998
annotation not available
   
 0.459
FAM126A
Family with sequence similarity 126 member A.
      
 0.457
FARSB
Phenylalanyl-tRNA synthetase subunit beta.
      
 0.454
BCDIN3D
BCDIN3 domain containing RNA methyltransferase.
    
 
 0.448
G1LAL2_AILME
Uncharacterized protein.
   
  
 0.443
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
   
  
 0.441
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.