CDK5RAP2 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CDK5RAP2

CDK5 regulatory subunit associated protein 2. (1901 aa)

Predicted Functional Partners:

PLK1

0.857

PPP1R16B

0.642

RWDD1

0.559

SLC22A7

0.529

PANK2

0.502

RNF24

0.486

TUBGCP6

0.478

CDHR3

0.471

TUBG1

0.466

TUBG2

0.466

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDHR3	CDK5RAP2	ENSAMEP00000014038	ENSAMEP00000001402	Cadherin related family member 3.	CDK5 regulatory subunit associated protein 2.	0.471
CDHR3	PPP1R16B	ENSAMEP00000014038	ENSAMEP00000012601	Cadherin related family member 3.	Protein phosphatase 1 regulatory subunit 16B.	0.468
CDHR3	RWDD1	ENSAMEP00000014038	ENSAMEP00000006017	Cadherin related family member 3.	RWD domain containing 1.	0.515
CDK5RAP2	CDHR3	ENSAMEP00000001402	ENSAMEP00000014038	CDK5 regulatory subunit associated protein 2.	Cadherin related family member 3.	0.471
CDK5RAP2	PANK2	ENSAMEP00000001402	ENSAMEP00000011243	CDK5 regulatory subunit associated protein 2.	Pantothenate kinase 2.	0.502
CDK5RAP2	PLK1	ENSAMEP00000001402	ENSAMEP00000015034	CDK5 regulatory subunit associated protein 2.	Serine/threonine-protein kinase PLK.	0.857
CDK5RAP2	PPP1R16B	ENSAMEP00000001402	ENSAMEP00000012601	CDK5 regulatory subunit associated protein 2.	Protein phosphatase 1 regulatory subunit 16B.	0.642
CDK5RAP2	RNF24	ENSAMEP00000001402	ENSAMEP00000011218	CDK5 regulatory subunit associated protein 2.	Ring finger protein 24.	0.486
CDK5RAP2	RWDD1	ENSAMEP00000001402	ENSAMEP00000006017	CDK5 regulatory subunit associated protein 2.	RWD domain containing 1.	0.559
CDK5RAP2	SLC22A7	ENSAMEP00000001402	ENSAMEP00000013022	CDK5 regulatory subunit associated protein 2.	Solute carrier family 22 member 7.	0.529
CDK5RAP2	TUBG1	ENSAMEP00000001402	ENSAMEP00000006986	CDK5 regulatory subunit associated protein 2.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.466
CDK5RAP2	TUBG2	ENSAMEP00000001402	ENSAMEP00000007015	CDK5 regulatory subunit associated protein 2.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.466
CDK5RAP2	TUBGCP6	ENSAMEP00000001402	ENSAMEP00000002518	CDK5 regulatory subunit associated protein 2.	Tubulin gamma complex associated protein 6.	0.478
PANK2	CDK5RAP2	ENSAMEP00000011243	ENSAMEP00000001402	Pantothenate kinase 2.	CDK5 regulatory subunit associated protein 2.	0.502
PANK2	PPP1R16B	ENSAMEP00000011243	ENSAMEP00000012601	Pantothenate kinase 2.	Protein phosphatase 1 regulatory subunit 16B.	0.449
PANK2	RNF24	ENSAMEP00000011243	ENSAMEP00000011218	Pantothenate kinase 2.	Ring finger protein 24.	0.690
PANK2	RWDD1	ENSAMEP00000011243	ENSAMEP00000006017	Pantothenate kinase 2.	RWD domain containing 1.	0.476
PLK1	CDK5RAP2	ENSAMEP00000015034	ENSAMEP00000001402	Serine/threonine-protein kinase PLK.	CDK5 regulatory subunit associated protein 2.	0.857
PLK1	TUBG1	ENSAMEP00000015034	ENSAMEP00000006986	Serine/threonine-protein kinase PLK.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.738
PLK1	TUBG2	ENSAMEP00000015034	ENSAMEP00000007015	Serine/threonine-protein kinase PLK.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.738