Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NSL1NSL1 component of MIS12 kinetochore complex. (280 aa)    
Predicted Functional Partners:
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.999
MIS12
MIS12 kinetochore complex component.
    
 0.997
LOC100469881
Uncharacterized protein.
    
 0.994
NDC80
NDC80 kinetochore complex component.
   
 0.993
SPC25
SPC25 component of NDC80 kinetochore complex.
   
 0.991
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.990
SPC24
SPC24 component of NDC80 kinetochore complex.
   
 0.988
ZWINT
ZW10 interacting kinetochore protein.
    
 0.985
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.975
CBX5
Chromobox 5.
    
 
 0.900
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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