Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPINK8Serine peptidase inhibitor, Kazal type 8 (putative). (92 aa)    
Predicted Functional Partners:
REG4
Regenerating family member 4.
      
 0.718
PNOC
Prepronociceptin.
      
 0.715
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
      
 0.591
USP43
Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.
      
 0.560
MTMR14
Myotubularin related protein 14.
      
 0.490
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
      
 0.436
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2.
      
 0.434
WDR7
WD repeat domain 7.
      
 0.427
FCGBP
Uncharacterized protein.
      
 0.410
BPIFA1
BPI fold containing family A member 1.
      
 0.410
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.