GLG1 protein (Ailuropoda melanoleuca) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

GLG1

Golgi glycoprotein 1. (1114 aa)

Predicted Functional Partners:

SELE

0.957

CCDC88A

0.813

C17orf75

0.750

FADD

0.701

FAM91A1

0.701

RFWD3

0.634

BTG3

0.631

WDR59

0.626

CASP8

0.614

SELP

0.543

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTG3	GLG1	ENSAMEP00000015318	ENSAMEP00000001441	BTG anti-proliferation factor 3.	Golgi glycoprotein 1.	0.631
C17orf75	FAM91A1	ENSAMEP00000005974	ENSAMEP00000011891	Chromosome 17 open reading frame 75.	Family with sequence similarity 91 member A1.	0.924
C17orf75	GLG1	ENSAMEP00000005974	ENSAMEP00000001441	Chromosome 17 open reading frame 75.	Golgi glycoprotein 1.	0.750
CASP8	FADD	ENSAMEP00000006404	ENSAMEP00000007570	Caspase 8; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.999
CASP8	GLG1	ENSAMEP00000006404	ENSAMEP00000001441	Caspase 8; Belongs to the peptidase C14A family.	Golgi glycoprotein 1.	0.614
CASP8	RFWD3	ENSAMEP00000006404	ENSAMEP00000001391	Caspase 8; Belongs to the peptidase C14A family.	E3 ubiquitin-protein ligase RFWD3; E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage. Plays a key role in RPA-mediated DNA damage signaling and repair. Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination. Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA [...]	0.463
CASP8	WDR59	ENSAMEP00000006404	ENSAMEP00000001366	Caspase 8; Belongs to the peptidase C14A family.	WD repeat domain 59.	0.463
CCDC88A	GLG1	ENSAMEP00000004190	ENSAMEP00000001441	Coiled-coil domain containing 88A.	Golgi glycoprotein 1.	0.813
FADD	CASP8	ENSAMEP00000007570	ENSAMEP00000006404	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 8; Belongs to the peptidase C14A family.	0.999
FADD	GLG1	ENSAMEP00000007570	ENSAMEP00000001441	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Golgi glycoprotein 1.	0.701
FADD	RFWD3	ENSAMEP00000007570	ENSAMEP00000001391	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	E3 ubiquitin-protein ligase RFWD3; E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage. Plays a key role in RPA-mediated DNA damage signaling and repair. Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination. Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA [...]	0.504
FADD	WDR59	ENSAMEP00000007570	ENSAMEP00000001366	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	WD repeat domain 59.	0.524
FAM91A1	C17orf75	ENSAMEP00000011891	ENSAMEP00000005974	Family with sequence similarity 91 member A1.	Chromosome 17 open reading frame 75.	0.924
FAM91A1	GLG1	ENSAMEP00000011891	ENSAMEP00000001441	Family with sequence similarity 91 member A1.	Golgi glycoprotein 1.	0.701
GLG1	BTG3	ENSAMEP00000001441	ENSAMEP00000015318	Golgi glycoprotein 1.	BTG anti-proliferation factor 3.	0.631
GLG1	C17orf75	ENSAMEP00000001441	ENSAMEP00000005974	Golgi glycoprotein 1.	Chromosome 17 open reading frame 75.	0.750
GLG1	CASP8	ENSAMEP00000001441	ENSAMEP00000006404	Golgi glycoprotein 1.	Caspase 8; Belongs to the peptidase C14A family.	0.614
GLG1	CCDC88A	ENSAMEP00000001441	ENSAMEP00000004190	Golgi glycoprotein 1.	Coiled-coil domain containing 88A.	0.813
GLG1	FADD	ENSAMEP00000001441	ENSAMEP00000007570	Golgi glycoprotein 1.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.701
GLG1	FAM91A1	ENSAMEP00000001441	ENSAMEP00000011891	Golgi glycoprotein 1.	Family with sequence similarity 91 member A1.	0.701