Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
SYNGAP1Synaptic Ras GTPase activating protein 1. (1322 aa)    
Predicted Functional Partners:
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
 
 0.942
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
 
 0.935
MRAS
Muscle RAS oncogene homolog.
    
 0.920
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 
 0.912
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 
 0.869
SHANK2
SH3 and multiple ankyrin repeat domains 2.
   
 
 0.864
DLGAP2
DLG associated protein 2.
   
 
 0.853
KRAS
KRAS proto-oncogene, GTPase.
    
 0.846
DLGAP3
DLG associated protein 3.
   
 
 0.845
RRAS
RAS related.
    
 0.845
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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