STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MNX1Motor neuron and pancreas homeobox 1. (225 aa)    
Predicted Functional Partners:
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
  
 0.635
LOC100477690
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
      
 0.622
FOXA2
Forkhead box A2.
    
 0.614
LHX3
LIM homeobox 3.
   
 
 0.548
RFX6
DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide- producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by [...]
      
 0.523
FAM131B
Family with sequence similarity 131 member B.
   
  
 0.482
ONECUT1
One cut domain family member.
     
 0.474
G1MK63_AILME
Homeobox domain-containing protein.
     
 0.474
ZIC4
Zic family member 4.
    
 
 0.461
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
   
  
 0.454
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.