DSTYK protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DSTYK

Dual serine/threonine and tyrosine protein kinase. (931 aa)

Predicted Functional Partners:

SPINK6

0.767

TIMM17A

0.754

BYSL

0.692

MED20

0.682

TMEM81

0.642

USP49

0.635

RBBP5

0.620

DBNDD1

0.582

FAXC

0.582

CYB5R2

0.581

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BYSL	DSTYK	ENSAMEP00000013726	ENSAMEP00000001480	Bystin like.	Dual serine/threonine and tyrosine protein kinase.	0.692
BYSL	MED20	ENSAMEP00000013726	ENSAMEP00000013741	Bystin like.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.649
BYSL	USP49	ENSAMEP00000013726	ENSAMEP00000013756	Bystin like.	Ubiquitinyl hydrolase 1.	0.769
CYB5R2	DSTYK	ENSAMEP00000004627	ENSAMEP00000001480	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Dual serine/threonine and tyrosine protein kinase.	0.581
DBNDD1	DSTYK	ENSAMEP00000001494	ENSAMEP00000001480	Uncharacterized protein.	Dual serine/threonine and tyrosine protein kinase.	0.582
DSTYK	BYSL	ENSAMEP00000001480	ENSAMEP00000013726	Dual serine/threonine and tyrosine protein kinase.	Bystin like.	0.692
DSTYK	CYB5R2	ENSAMEP00000001480	ENSAMEP00000004627	Dual serine/threonine and tyrosine protein kinase.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.581
DSTYK	DBNDD1	ENSAMEP00000001480	ENSAMEP00000001494	Dual serine/threonine and tyrosine protein kinase.	Uncharacterized protein.	0.582
DSTYK	FAXC	ENSAMEP00000001480	ENSAMEP00000011820	Dual serine/threonine and tyrosine protein kinase.	Failed axon connections homolog, metaxin like GST domain containing.	0.582
DSTYK	MED20	ENSAMEP00000001480	ENSAMEP00000013741	Dual serine/threonine and tyrosine protein kinase.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.682
DSTYK	RBBP5	ENSAMEP00000001480	ENSAMEP00000001417	Dual serine/threonine and tyrosine protein kinase.	RB binding protein 5, histone lysine methyltransferase complex subunit.	0.620
DSTYK	SPINK6	ENSAMEP00000001480	ENSAMEP00000009961	Dual serine/threonine and tyrosine protein kinase.	Serine peptidase inhibitor, Kazal type 6.	0.767
DSTYK	TIMM17A	ENSAMEP00000001480	ENSAMEP00000012668	Dual serine/threonine and tyrosine protein kinase.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.754
DSTYK	TMEM81	ENSAMEP00000001480	ENSAMEP00000020936	Dual serine/threonine and tyrosine protein kinase.	Transmembrane protein 81.	0.642
DSTYK	USP49	ENSAMEP00000001480	ENSAMEP00000013756	Dual serine/threonine and tyrosine protein kinase.	Ubiquitinyl hydrolase 1.	0.635
FAXC	DSTYK	ENSAMEP00000011820	ENSAMEP00000001480	Failed axon connections homolog, metaxin like GST domain containing.	Dual serine/threonine and tyrosine protein kinase.	0.582
MED20	BYSL	ENSAMEP00000013741	ENSAMEP00000013726	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Bystin like.	0.649
MED20	DSTYK	ENSAMEP00000013741	ENSAMEP00000001480	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Dual serine/threonine and tyrosine protein kinase.	0.682
MED20	USP49	ENSAMEP00000013741	ENSAMEP00000013756	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Ubiquitinyl hydrolase 1.	0.599
RBBP5	DSTYK	ENSAMEP00000001417	ENSAMEP00000001480	RB binding protein 5, histone lysine methyltransferase complex subunit.	Dual serine/threonine and tyrosine protein kinase.	0.620