Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEF8Differentially expressed in FDCP 8 homolog. (459 aa)    
Predicted Functional Partners:
TCF25
Transcription factor 25.
      
 0.693
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1.
   
  
 0.625
UVRAG
UV radiation resistance associated.
    
 0.611
ABI3
ABI family member 3.
      
 0.602
RRBP1
Ribosome binding protein 1.
      
 0.568
MTHFSD
Methenyltetrahydrofolate synthetase domain containing.
      
 0.568
ZNF276
Zinc finger protein 276.
      
 0.566
PDCD5
Programmed cell death 5.
      
 0.566
TREML2
Ig-like domain-containing protein.
   
  
 0.558
PRSS8
Uncharacterized protein; Belongs to the peptidase S1 family.
      
 0.555
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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