Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STK40Serine/threonine kinase 40. (445 aa)    
Predicted Functional Partners:
TRIB3
Tribbles pseudokinase 3.
    
 
 0.937
TRIB1
Tribbles pseudokinase 1.
    
 
 0.933
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.933
ETV1
ETS variant 1.
    
   0.932
ETV5
ETS variant 5.
    
   0.932
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.850
TRIB2
Tribbles pseudokinase 2.
    
 
 0.825
FOSL2
FOS like 2, AP-1 transcription factor subunit.
   
 0.823
DET1
Uncharacterized protein.
   
 
 0.818
NFIL3
Nuclear factor, interleukin 3 regulated.
   
 0.813
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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