Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1034 aa)    
Predicted Functional Partners:
G1LAT3_AILME
Pep_M12B_propep domain-containing protein.
 
      0.871
ACAN
Aggrecan.
    
 0.735
CCBE1
Collagen and calcium binding EGF domains 1.
      
 0.731
CX3CL1
C-X3-C motif chemokine ligand 1.
    
 0.722
VIPR1
Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.
      
 0.715
GDF15
Growth differentiation factor 15.
      
 0.714
LOX
Lysyl oxidase.
   
 0.696
MMP13
Matrix metallopeptidase 13.
   
 
 0.656
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
 
 0.601
CCDC171
Coiled-coil domain containing 171.
    
 0.575
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (22%) [HD]