STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1034 aa)    
Predicted Functional Partners:
G1LAT3_AILME
Pep_M12B_propep domain-containing protein.
 
      0.871
CCBE1
Collagen and calcium binding EGF domains 1.
      
 0.825
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
  
 0.705
TMEM86A
Transmembrane protein 86A.
   
  
 0.600
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
   
 0.566
HINT2
Histidine triad nucleotide binding protein 2.
      
 0.523
GET3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
      
 0.503
ACAN
Aggrecan.
    
 0.474
CPXM1
Carboxypeptidase X, M14 family member 1.
   
  
 0.470
SLC35F1
Solute carrier family 35 member F1.
   
  
 0.456
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.