Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (470 aa)    
Predicted Functional Partners:
EPRS1
Glutamyl-prolyl-tRNA synthetase.
    
 
 0.650
WNT8B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.613
SLC35F3
Solute carrier family 35 member F3.
      
 0.605
SIGMAR1
Sigma non-opioid intracellular receptor 1.
    
 
 0.585
FAM210B
Family with sequence similarity 210 member B.
      
 0.573
QSOX2
Sulfhydryl oxidase.
    
 
 0.572
TSEN2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
      
 0.571
MCTP1
Multiple C2 and transmembrane domain containing 1.
      
 0.549
MB21D2
Mab-21 domain containing 2.
      
 0.543
G1MKY5_AILME
Uncharacterized protein.
    
 
 0.541
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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