Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO1Roundabout guidance receptor 1. (1593 aa)    
Predicted Functional Partners:
SLIT2
Slit guidance ligand 2.
   
 0.939
SLIT1
Slit guidance ligand 1.
   
 0.938
ABL2
Tyrosine-protein kinase.
   
 0.822
ABL1
Tyrosine-protein kinase.
   
 0.822
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3.
    
 0.805
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1.
    
 0.790
NCK2
NCK adaptor protein 2.
    
 0.789
PAK5
Non-specific serine/threonine protein kinase.
   
 0.761
PAK6
Non-specific serine/threonine protein kinase.
   
 0.757
ROBO3
Roundabout guidance receptor 3.
    
 0.754
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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