PRDM1 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

PRDM1

PR/SET domain 1. (861 aa)

Predicted Functional Partners:

TFAP2C

0.895

EHMT2

0.849

SOX17

0.833

BMX

0.824

KIZ

0.749

NANOS3

0.720

FBXO11

0.718

TP53

0.711

FANCM

0.705

HDAC1

0.701

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMX	KIZ	ENSAMEP00000016791	ENSAMEP00000013229	Tyrosine-protein kinase.	Kizuna centrosomal protein.	0.744
BMX	PRDM1	ENSAMEP00000016791	ENSAMEP00000001570	Tyrosine-protein kinase.	PR/SET domain 1.	0.824
EHMT2	HDAC1	ENSAMEP00000013634	ENSAMEP00000008076	Euchromatic histone lysine methyltransferase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.829
EHMT2	PRDM1	ENSAMEP00000013634	ENSAMEP00000001570	Euchromatic histone lysine methyltransferase 2.	PR/SET domain 1.	0.849
EHMT2	TP53	ENSAMEP00000013634	ENSAMEP00000017825	Euchromatic histone lysine methyltransferase 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.883
FANCM	KIZ	ENSAMEP00000002260	ENSAMEP00000013229	FA complementation group M.	Kizuna centrosomal protein.	0.739
FANCM	PRDM1	ENSAMEP00000002260	ENSAMEP00000001570	FA complementation group M.	PR/SET domain 1.	0.705
FBXO11	PRDM1	ENSAMEP00000006740	ENSAMEP00000001570	F-box protein 11.	PR/SET domain 1.	0.718
FBXO11	TP53	ENSAMEP00000006740	ENSAMEP00000017825	F-box protein 11.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.695
HDAC1	EHMT2	ENSAMEP00000008076	ENSAMEP00000013634	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Euchromatic histone lysine methyltransferase 2.	0.829
HDAC1	PRDM1	ENSAMEP00000008076	ENSAMEP00000001570	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	PR/SET domain 1.	0.701
HDAC1	TP53	ENSAMEP00000008076	ENSAMEP00000017825	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.887
KIZ	BMX	ENSAMEP00000013229	ENSAMEP00000016791	Kizuna centrosomal protein.	Tyrosine-protein kinase.	0.744
KIZ	FANCM	ENSAMEP00000013229	ENSAMEP00000002260	Kizuna centrosomal protein.	FA complementation group M.	0.739
KIZ	PRDM1	ENSAMEP00000013229	ENSAMEP00000001570	Kizuna centrosomal protein.	PR/SET domain 1.	0.749
NANOS3	PRDM1	ENSAMEP00000013651	ENSAMEP00000001570	Nanos C2HC-type zinc finger 3; Belongs to the nanos family.	PR/SET domain 1.	0.720
NANOS3	SOX17	ENSAMEP00000013651	ENSAMEP00000012278	Nanos C2HC-type zinc finger 3; Belongs to the nanos family.	SRY-box transcription factor 17.	0.610
NANOS3	TFAP2C	ENSAMEP00000013651	ENSAMEP00000007430	Nanos C2HC-type zinc finger 3; Belongs to the nanos family.	Transcription factor AP-2 gamma.	0.655
PRDM1	BMX	ENSAMEP00000001570	ENSAMEP00000016791	PR/SET domain 1.	Tyrosine-protein kinase.	0.824
PRDM1	EHMT2	ENSAMEP00000001570	ENSAMEP00000013634	PR/SET domain 1.	Euchromatic histone lysine methyltransferase 2.	0.849