SZT2 protein (Ailuropoda melanoleuca) - STRING interaction network

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SZT2

SZT2 subunit of KICSTOR complex. (3423 aa)

Predicted Functional Partners:

C12orf66

0.997

ITFG2

0.994

KPTN

0.993

DEPDC5

0.983

NPRL3

0.982

WDR24

0.982

WDR59

0.981

NPRL2

0.980

LAMP1

0.932

BMT2

0.921

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C12orf66	ENSAMEP00000005925	ENSAMEP00000019126	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 12 open reading frame 66.	0.949
BMT2	DEPDC5	ENSAMEP00000005925	ENSAMEP00000007362	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.960
BMT2	ITFG2	ENSAMEP00000005925	ENSAMEP00000005120	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat containing 2.	0.952
BMT2	KPTN	ENSAMEP00000005925	ENSAMEP00000008588	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin, actin binding protein.	0.933
BMT2	NPRL2	ENSAMEP00000005925	ENSAMEP00000012261	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.852
BMT2	NPRL3	ENSAMEP00000005925	ENSAMEP00000007228	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR3 like, GATOR1 complex subunit.	0.868
BMT2	SZT2	ENSAMEP00000005925	ENSAMEP00000001672	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	SZT2 subunit of KICSTOR complex.	0.921
BMT2	WDR59	ENSAMEP00000005925	ENSAMEP00000001366	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.410
C12orf66	BMT2	ENSAMEP00000019126	ENSAMEP00000005925	Chromosome 12 open reading frame 66.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.949
C12orf66	DEPDC5	ENSAMEP00000019126	ENSAMEP00000007362	Chromosome 12 open reading frame 66.	DEP domain-containing protein.	0.989
C12orf66	ITFG2	ENSAMEP00000019126	ENSAMEP00000005120	Chromosome 12 open reading frame 66.	Integrin alpha FG-GAP repeat containing 2.	0.999
C12orf66	KPTN	ENSAMEP00000019126	ENSAMEP00000008588	Chromosome 12 open reading frame 66.	Kaptin, actin binding protein.	0.997
C12orf66	NPRL2	ENSAMEP00000019126	ENSAMEP00000012261	Chromosome 12 open reading frame 66.	NPR2 like, GATOR1 complex subunit.	0.987
C12orf66	NPRL3	ENSAMEP00000019126	ENSAMEP00000007228	Chromosome 12 open reading frame 66.	NPR3 like, GATOR1 complex subunit.	0.917
C12orf66	SZT2	ENSAMEP00000019126	ENSAMEP00000001672	Chromosome 12 open reading frame 66.	SZT2 subunit of KICSTOR complex.	0.997
C12orf66	WDR24	ENSAMEP00000019126	ENSAMEP00000007746	Chromosome 12 open reading frame 66.	WD repeat domain 24.	0.992
C12orf66	WDR59	ENSAMEP00000019126	ENSAMEP00000001366	Chromosome 12 open reading frame 66.	WD repeat domain 59.	0.987
DEPDC5	BMT2	ENSAMEP00000007362	ENSAMEP00000005925	DEP domain-containing protein.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.960
DEPDC5	C12orf66	ENSAMEP00000007362	ENSAMEP00000019126	DEP domain-containing protein.	Chromosome 12 open reading frame 66.	0.989
DEPDC5	ITFG2	ENSAMEP00000007362	ENSAMEP00000005120	DEP domain-containing protein.	Integrin alpha FG-GAP repeat containing 2.	0.981