Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPATA46Spermatogenesis associated 46. (247 aa)    
Predicted Functional Partners:
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
    
   0.808
SNX24
Sorting nexin 24.
    
   0.808
GAPVD1
GTPase activating protein and VPS9 domains 1.
    
   0.808
HLCS
Holocarboxylase synthetase.
    
   0.803
CSNK1A1
Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.
    
   0.767
SSMEM1
Serine rich single-pass membrane protein 1.
      
 0.699
SNX22
Sorting nexin 22.
    
   0.682
SPACA1
Sperm acrosome associated 1.
   
  
 0.653
IZUMO3
Uncharacterized protein.
   
  
 0.620
SPATA16
Spermatogenesis associated 16.
   
  
 0.605
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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