MRGPRF protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MRGPRF

MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family. (343 aa)

Predicted Functional Partners:

CNN1

0.820

ZDHHC13

0.747

EFEMP2

0.675

FKBP10

0.663

COPZ2

0.653

PRRX2

0.645

VGLL3

0.615

ATOH8

0.591

TGFB1I1

0.577

PRSS23

0.570

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH8	COPZ2	ENSAMEP00000006097	ENSAMEP00000005142	Atonal bHLH transcription factor 8.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.555
ATOH8	EFEMP2	ENSAMEP00000006097	ENSAMEP00000018284	Atonal bHLH transcription factor 8.	EGF containing fibulin extracellular matrix protein 2.	0.587
ATOH8	FKBP10	ENSAMEP00000006097	ENSAMEP00000006057	Atonal bHLH transcription factor 8.	Peptidylprolyl isomerase.	0.590
ATOH8	MRGPRF	ENSAMEP00000006097	ENSAMEP00000001701	Atonal bHLH transcription factor 8.	MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.	0.591
ATOH8	PRRX2	ENSAMEP00000006097	ENSAMEP00000016900	Atonal bHLH transcription factor 8.	Paired related homeobox 2.	0.603
ATOH8	PRSS23	ENSAMEP00000006097	ENSAMEP00000020471	Atonal bHLH transcription factor 8.	Serine protease; Belongs to the peptidase S1B family.	0.524
ATOH8	TGFB1I1	ENSAMEP00000006097	ENSAMEP00000017168	Atonal bHLH transcription factor 8.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.529
ATOH8	VGLL3	ENSAMEP00000006097	ENSAMEP00000007647	Atonal bHLH transcription factor 8.	Vestigial like family member 3.	0.581
CNN1	MRGPRF	ENSAMEP00000000061	ENSAMEP00000001701	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.	0.820
COPZ2	ATOH8	ENSAMEP00000005142	ENSAMEP00000006097	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Atonal bHLH transcription factor 8.	0.555
COPZ2	EFEMP2	ENSAMEP00000005142	ENSAMEP00000018284	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	EGF containing fibulin extracellular matrix protein 2.	0.725
COPZ2	FKBP10	ENSAMEP00000005142	ENSAMEP00000006057	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Peptidylprolyl isomerase.	0.669
COPZ2	MRGPRF	ENSAMEP00000005142	ENSAMEP00000001701	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.	0.653
COPZ2	PRRX2	ENSAMEP00000005142	ENSAMEP00000016900	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Paired related homeobox 2.	0.590
COPZ2	PRSS23	ENSAMEP00000005142	ENSAMEP00000020471	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Serine protease; Belongs to the peptidase S1B family.	0.527
COPZ2	TGFB1I1	ENSAMEP00000005142	ENSAMEP00000017168	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.594
COPZ2	VGLL3	ENSAMEP00000005142	ENSAMEP00000007647	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Vestigial like family member 3.	0.670
EFEMP2	ATOH8	ENSAMEP00000018284	ENSAMEP00000006097	EGF containing fibulin extracellular matrix protein 2.	Atonal bHLH transcription factor 8.	0.587
EFEMP2	COPZ2	ENSAMEP00000018284	ENSAMEP00000005142	EGF containing fibulin extracellular matrix protein 2.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.725
EFEMP2	FKBP10	ENSAMEP00000018284	ENSAMEP00000006057	EGF containing fibulin extracellular matrix protein 2.	Peptidylprolyl isomerase.	0.871