RPRD2 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RPRD2

Regulation of nuclear pre-mRNA domain containing 2. (1463 aa)

Predicted Functional Partners:

RPRD1B

0.987

RPAP2

0.982

RPRD1A

0.974

POLR2G

0.973

SUPT5H

0.890

POLR2C

0.831

POLR2E

0.818

PCF11

0.812

POLR2I

0.809

POLR2B

0.806

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PCF11	POLR2B	ENSAMEP00000005568	ENSAMEP00000009051	PCF11 cleavage and polyadenylation factor subunit.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.790
PCF11	POLR2C	ENSAMEP00000005568	ENSAMEP00000017994	PCF11 cleavage and polyadenylation factor subunit.	RNA polymerase II subunit C.	0.840
PCF11	POLR2E	ENSAMEP00000005568	ENSAMEP00000003341	PCF11 cleavage and polyadenylation factor subunit.	RNA polymerase II subunit E.	0.841
PCF11	POLR2G	ENSAMEP00000005568	ENSAMEP00000006746	PCF11 cleavage and polyadenylation factor subunit.	RNA polymerase II subunit G.	0.628
PCF11	POLR2I	ENSAMEP00000005568	ENSAMEP00000001043	PCF11 cleavage and polyadenylation factor subunit.	RNA polymerase II subunit I; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.845
PCF11	RPAP2	ENSAMEP00000005568	ENSAMEP00000014615	PCF11 cleavage and polyadenylation factor subunit.	RNA polymerase II associated protein 2.	0.700
PCF11	RPRD1A	ENSAMEP00000005568	ENSAMEP00000000867	PCF11 cleavage and polyadenylation factor subunit.	Regulation of nuclear pre-mRNA domain containing 1A.	0.769
PCF11	RPRD1B	ENSAMEP00000005568	ENSAMEP00000012894	PCF11 cleavage and polyadenylation factor subunit.	Regulation of nuclear pre-mRNA domain containing 1B.	0.611
PCF11	RPRD2	ENSAMEP00000005568	ENSAMEP00000001702	PCF11 cleavage and polyadenylation factor subunit.	Regulation of nuclear pre-mRNA domain containing 2.	0.812
PCF11	SUPT5H	ENSAMEP00000005568	ENSAMEP00000008901	PCF11 cleavage and polyadenylation factor subunit.	Transcription elongation factor SPT5.	0.526
POLR2B	PCF11	ENSAMEP00000009051	ENSAMEP00000005568	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	PCF11 cleavage and polyadenylation factor subunit.	0.790
POLR2B	POLR2C	ENSAMEP00000009051	ENSAMEP00000017994	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit C.	0.999
POLR2B	POLR2E	ENSAMEP00000009051	ENSAMEP00000003341	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit E.	0.999
POLR2B	POLR2G	ENSAMEP00000009051	ENSAMEP00000006746	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit G.	0.998
POLR2B	POLR2I	ENSAMEP00000009051	ENSAMEP00000001043	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit I; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.998
POLR2B	RPAP2	ENSAMEP00000009051	ENSAMEP00000014615	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II associated protein 2.	0.932
POLR2B	RPRD1A	ENSAMEP00000009051	ENSAMEP00000000867	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Regulation of nuclear pre-mRNA domain containing 1A.	0.849
POLR2B	RPRD1B	ENSAMEP00000009051	ENSAMEP00000012894	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Regulation of nuclear pre-mRNA domain containing 1B.	0.963
POLR2B	RPRD2	ENSAMEP00000009051	ENSAMEP00000001702	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Regulation of nuclear pre-mRNA domain containing 2.	0.806
POLR2B	SUPT5H	ENSAMEP00000009051	ENSAMEP00000008901	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor SPT5.	0.967