Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC20Cell division cycle 20. (499 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.995
BUB1B
BUB1 N-terminal domain-containing protein.
   
 0.995
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.993
PTTG1
Uncharacterized protein.
   
 0.992
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.986
CDC27
Cell division cycle 27.
   
 0.986
UBE2C
Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.985
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.983
NEK2
NIMA related kinase 2.
   
 0.980
MAD2L1
HORMA domain-containing protein.
   
 0.980
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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