Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G1L4E2_AILMEIF rod domain-containing protein; Belongs to the intermediate filament family. (489 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.622
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
     
  0.550
KRT39
Keratin 39; Belongs to the intermediate filament family.
    
 0.497
DSG3
Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
     
  0.444
DSG2
Desmoglein 2.
     
  0.444
KRT85
Keratin 85; Belongs to the intermediate filament family.
   
  0.439
NBR1
NBR1 autophagy cargo receptor.
   
 0.434
KRT82
Keratin 82; Belongs to the intermediate filament family.
   
  0.427
KRT84
Keratin 84; Belongs to the intermediate filament family.
   
  0.415
NME8
NME/NM23 family member 8.
   
 0.412
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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