Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
COMTD1Catechol-O-methyltransferase domain containing 1. (262 aa)    
Predicted Functional Partners:
DUS2
Dihydrouridine synthase 2.
   
  
 0.723
COPRS
Coordinator of PRMT5 and differentiation stimulator.
      
 0.673
PAXBP1
PAX3 and PAX7 binding protein 1.
      
 0.667
MAP6D1
MAP6 domain containing 1.
    
 
 0.629
TMC4
Transmembrane channel-like protein.
      
 0.604
MRTFA
Myocardin related transcription factor A.
  
 
 0.604
RCN2
Reticulocalbin 2.
      
 0.600
TK1
Thymidine kinase.
  
 
  0.597
NAXE
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
      
 0.569
TBC1D14
TBC1 domain family member 14.
      
 0.557
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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