RXRB protein (Ailuropoda melanoleuca) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

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[Homology]

Score

RXRB

Retinoid X receptor beta. (536 aa)

Predicted Functional Partners:

NCOA2

0.996

RARB

0.986

PPARG

0.976

NR1H3

0.975

RXRA

0.944

RXRG

0.937

PPARD

0.932

RARA

0.921

MED1

0.907

PAX8

0.906

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED1	NCOA2	ENSAMEP00000004219	ENSAMEP00000006644	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.555
MED1	NR1H3	ENSAMEP00000004219	ENSAMEP00000007697	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 3.	0.705
MED1	PPARD	ENSAMEP00000004219	ENSAMEP00000000742	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator activated receptor delta.	0.578
MED1	PPARG	ENSAMEP00000004219	ENSAMEP00000005049	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.956
MED1	RARA	ENSAMEP00000004219	ENSAMEP00000008395	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoic acid receptor alpha.	0.699
MED1	RARB	ENSAMEP00000004219	ENSAMEP00000000771	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoic acid receptor beta.	0.612
MED1	RXRA	ENSAMEP00000004219	ENSAMEP00000011750	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor alpha.	0.916
MED1	RXRB	ENSAMEP00000004219	ENSAMEP00000001817	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor beta.	0.907
MED1	RXRG	ENSAMEP00000004219	ENSAMEP00000006999	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor gamma.	0.916
NCOA2	MED1	ENSAMEP00000006644	ENSAMEP00000004219	Nuclear receptor coactivator.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.555
NCOA2	NR1H3	ENSAMEP00000006644	ENSAMEP00000007697	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.861
NCOA2	PPARD	ENSAMEP00000006644	ENSAMEP00000000742	Nuclear receptor coactivator.	Peroxisome proliferator activated receptor delta.	0.431
NCOA2	PPARG	ENSAMEP00000006644	ENSAMEP00000005049	Nuclear receptor coactivator.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.900
NCOA2	RARA	ENSAMEP00000006644	ENSAMEP00000008395	Nuclear receptor coactivator.	Retinoic acid receptor alpha.	0.523
NCOA2	RARB	ENSAMEP00000006644	ENSAMEP00000000771	Nuclear receptor coactivator.	Retinoic acid receptor beta.	0.520
NCOA2	RXRA	ENSAMEP00000006644	ENSAMEP00000011750	Nuclear receptor coactivator.	Retinoid X receptor alpha.	0.989
NCOA2	RXRB	ENSAMEP00000006644	ENSAMEP00000001817	Nuclear receptor coactivator.	Retinoid X receptor beta.	0.996
NCOA2	RXRG	ENSAMEP00000006644	ENSAMEP00000006999	Nuclear receptor coactivator.	Retinoid X receptor gamma.	0.942
NR1H3	MED1	ENSAMEP00000007697	ENSAMEP00000004219	Nuclear receptor subfamily 1 group H member 3.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.705
NR1H3	NCOA2	ENSAMEP00000007697	ENSAMEP00000006644	Nuclear receptor subfamily 1 group H member 3.	Nuclear receptor coactivator.	0.861