RXRB protein (Ailuropoda melanoleuca) - STRING interaction network

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[Homology]

Score

RXRB

Retinoid X receptor beta. (536 aa)

Predicted Functional Partners:

PPARG

0.982

NCOA2

0.980

PPARA

0.970

MED1

0.962

PPARD

0.960

NR1H3

0.959

RARA

0.952

NR1H2

0.949

RXRG

0.934

RXRA

0.934

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED1	NCOA2	ENSAMEP00000004219	ENSAMEP00000006644	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.700
MED1	NR1H2	ENSAMEP00000004219	ENSAMEP00000013937	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 2.	0.676
MED1	NR1H3	ENSAMEP00000004219	ENSAMEP00000007697	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 3.	0.676
MED1	PPARA	ENSAMEP00000004219	ENSAMEP00000003616	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator activated receptor alpha.	0.945
MED1	PPARD	ENSAMEP00000004219	ENSAMEP00000000742	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator activated receptor delta.	0.628
MED1	PPARG	ENSAMEP00000004219	ENSAMEP00000005049	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.975
MED1	RARA	ENSAMEP00000004219	ENSAMEP00000008395	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoic acid receptor alpha.	0.720
MED1	RXRA	ENSAMEP00000004219	ENSAMEP00000011750	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor alpha.	0.955
MED1	RXRB	ENSAMEP00000004219	ENSAMEP00000001817	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor beta.	0.962
MED1	RXRG	ENSAMEP00000004219	ENSAMEP00000006999	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor gamma.	0.955
NCOA2	MED1	ENSAMEP00000006644	ENSAMEP00000004219	Nuclear receptor coactivator.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.700
NCOA2	NR1H2	ENSAMEP00000006644	ENSAMEP00000013937	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 2.	0.862
NCOA2	NR1H3	ENSAMEP00000006644	ENSAMEP00000007697	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.862
NCOA2	PPARA	ENSAMEP00000006644	ENSAMEP00000003616	Nuclear receptor coactivator.	Peroxisome proliferator activated receptor alpha.	0.778
NCOA2	PPARD	ENSAMEP00000006644	ENSAMEP00000000742	Nuclear receptor coactivator.	Peroxisome proliferator activated receptor delta.	0.653
NCOA2	PPARG	ENSAMEP00000006644	ENSAMEP00000005049	Nuclear receptor coactivator.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.898
NCOA2	RARA	ENSAMEP00000006644	ENSAMEP00000008395	Nuclear receptor coactivator.	Retinoic acid receptor alpha.	0.560
NCOA2	RXRA	ENSAMEP00000006644	ENSAMEP00000011750	Nuclear receptor coactivator.	Retinoid X receptor alpha.	0.956
NCOA2	RXRB	ENSAMEP00000006644	ENSAMEP00000001817	Nuclear receptor coactivator.	Retinoid X receptor beta.	0.980
NCOA2	RXRG	ENSAMEP00000006644	ENSAMEP00000006999	Nuclear receptor coactivator.	Retinoid X receptor gamma.	0.956