STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT80Keratin 80; Belongs to the intermediate filament family. (452 aa)    
Predicted Functional Partners:
KRTAP3-1
Keratin associated protein 3-1.
      
 0.632
KLK14
Kallikrein related peptidase 14; Belongs to the peptidase S1 family.
      
 0.562
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.536
KRTDAP
Keratinocyte differentiation associated protein.
      
 0.497
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.457
C11orf86
Chromosome 11 open reading frame 86.
      
 0.457
KLK12
Kallikrein related peptidase 12; Belongs to the peptidase S1 family.
      
 0.452
G1LBM0_AILME
Uncharacterized protein.
      
 0.449
PIK3AP1
Phosphoinositide-3-kinase adaptor protein 1.
      
 0.448
KRT32
Keratin 32; Belongs to the intermediate filament family.
  
 
0.447
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.