CAD protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CAD

Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2225 aa)

Predicted Functional Partners:

DHODH

0.985

ASS1

0.980

OTC

0.972

PPAT

0.967

GLS

0.950

ADSS2

0.941

GLUL

0.933

GFPT2

0.927

GFPT1

0.927

ASNS

0.927

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSS2	ASNS	ENSAMEP00000009733	ENSAMEP00000017268	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Asparagine synthetase (glutamine-hydrolyzing).	0.929
ADSS2	ASS1	ENSAMEP00000009733	ENSAMEP00000017086	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Argininosuccinate synthase 1.	0.948
ADSS2	CAD	ENSAMEP00000009733	ENSAMEP00000001870	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.941
ADSS2	DHODH	ENSAMEP00000009733	ENSAMEP00000002674	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.582
ADSS2	PPAT	ENSAMEP00000009733	ENSAMEP00000008874	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Phosphoribosyl pyrophosphate amidotransferase.	0.752
ASNS	ADSS2	ENSAMEP00000017268	ENSAMEP00000009733	Asparagine synthetase (glutamine-hydrolyzing).	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.929
ASNS	ASS1	ENSAMEP00000017268	ENSAMEP00000017086	Asparagine synthetase (glutamine-hydrolyzing).	Argininosuccinate synthase 1.	0.950
ASNS	CAD	ENSAMEP00000017268	ENSAMEP00000001870	Asparagine synthetase (glutamine-hydrolyzing).	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.927
ASNS	GFPT1	ENSAMEP00000017268	ENSAMEP00000017130	Asparagine synthetase (glutamine-hydrolyzing).	Glutamine--fructose-6-phosphate transaminase 1.	0.482
ASNS	GFPT2	ENSAMEP00000017268	ENSAMEP00000000971	Asparagine synthetase (glutamine-hydrolyzing).	Glutamine-fructose-6-phosphate transaminase 2.	0.482
ASNS	GLUL	ENSAMEP00000017268	ENSAMEP00000008130	Asparagine synthetase (glutamine-hydrolyzing).	Glutamine synthetase.	0.758
ASNS	PPAT	ENSAMEP00000017268	ENSAMEP00000008874	Asparagine synthetase (glutamine-hydrolyzing).	Phosphoribosyl pyrophosphate amidotransferase.	0.590
ASS1	ADSS2	ENSAMEP00000017086	ENSAMEP00000009733	Argininosuccinate synthase 1.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.948
ASS1	ASNS	ENSAMEP00000017086	ENSAMEP00000017268	Argininosuccinate synthase 1.	Asparagine synthetase (glutamine-hydrolyzing).	0.950
ASS1	CAD	ENSAMEP00000017086	ENSAMEP00000001870	Argininosuccinate synthase 1.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.980
ASS1	GLUL	ENSAMEP00000017086	ENSAMEP00000008130	Argininosuccinate synthase 1.	Glutamine synthetase.	0.493
ASS1	OTC	ENSAMEP00000017086	ENSAMEP00000007534	Argininosuccinate synthase 1.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.996
ASS1	PPAT	ENSAMEP00000017086	ENSAMEP00000008874	Argininosuccinate synthase 1.	Phosphoribosyl pyrophosphate amidotransferase.	0.562
CAD	ADSS2	ENSAMEP00000001870	ENSAMEP00000009733	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.941
CAD	ASNS	ENSAMEP00000001870	ENSAMEP00000017268	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Asparagine synthetase (glutamine-hydrolyzing).	0.927