Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
SH3BP4SH3 domain binding protein 4. (971 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 
 0.804
TMEM82
Transmembrane protein 82.
      
 0.694
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
   0.609
NTAN1
N-terminal asparagine amidase.
      
 0.597
WAS
WASP actin nucleation promoting factor.
   
  
 0.591
MNAT1
MNAT1 component of CDK activating kinase.
      
 0.568
DTYMK
Deoxythymidylate kinase.
      
 0.568
GAREM1
GRB2 associated regulator of MAPK1 subtype 1.
   
  
 0.562
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 
 0.548
CHST1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.537
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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