STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEF1Lymphoid enhancer binding factor 1. (399 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.998
NLK
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.995
TLE1
TLE family member 1, transcriptional corepressor.
    
 0.977
TCF7L2
Transcription factor 7 like 2.
   
0.971
SMAD4
Mothers against decapentaplegic homolog.
    
 0.970
AXIN2
Axin 2.
   
 0.964
TCF7
Transcription factor 7.
   
0.957
JUP
Junction plakoglobin.
    
 0.956
TCF7L1
Transcription factor 7 like 1.
  
0.950
CREBBP
CREB binding protein.
   
 0.940
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.