Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G1L4U1_AILMEExonuclease domain-containing protein. (431 aa)    
Predicted Functional Partners:
REXO2
RNA exonuclease 2.
   
 0.809
REXO5
RNA exonuclease 5.
     
 0.712
PAN3
Poly(A) specific ribonuclease subunit PAN3.
    
 0.531
EXOSC10
Exosome component 10.
   
 0.518
DDX51
DEAD-box helicase 51; Belongs to the DEAD box helicase family.
   
 0.511
TBL2
Transducin beta like 2.
   
  0.487
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.481
IZUMO1
Izumo sperm-egg fusion 1.
   
  
 0.462
WDR61
WD repeat domain 61.
      
 0.459
C1D
C1D nuclear receptor corepressor.
   
 
 0.440
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (12%) [HD]