Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2063 aa)    
Predicted Functional Partners:
MPP5
Membrane palmitoylated protein 5.
   
 0.990
AMOT
Angiomotin.
    
 0.984
AMOTL1
Angiomotin like 1.
    
 0.950
AMOTL2
Angiomotin like 2.
   
 0.935
CRB3
Crumbs cell polarity complex component 3.
    
 0.846
HTR2C
5-hydroxytryptamine receptor 2C.
    
 
 0.826
SUOX
Sulfite oxidase.
     
  0.775
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
 0.775
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.734
PARD3
Uncharacterized protein.
    
 0.670
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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