CRHBP protein (Ailuropoda melanoleuca) - STRING interaction network

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CRHBP

Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)

Predicted Functional Partners:

UCN

0.839

G1M7R8_AILME

0.721

CRHR2

0.680

MNT

0.614

SLC17A3

0.568

KITLG

0.549

BDNF

0.519

HMGCR

0.490

CHGB

0.490

COA7

0.437

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	CRHBP	ENSAMEP00000015321	ENSAMEP00000001924	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.519
BDNF	CRHR2	ENSAMEP00000015321	ENSAMEP00000007077	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.427
BDNF	G1M7R8_AILME	ENSAMEP00000015321	ENSAMEP00000015388	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.427
BDNF	HMGCR	ENSAMEP00000015321	ENSAMEP00000000725	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.426
CHGB	CRHBP	ENSAMEP00000010714	ENSAMEP00000001924	Chromogranin B.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.490
CHGB	HMGCR	ENSAMEP00000010714	ENSAMEP00000000725	Chromogranin B.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.492
COA7	CRHBP	ENSAMEP00000009868	ENSAMEP00000001924	Cytochrome c oxidase assembly factor 7 (putative).	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.437
CRHBP	BDNF	ENSAMEP00000001924	ENSAMEP00000015321	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.519
CRHBP	CHGB	ENSAMEP00000001924	ENSAMEP00000010714	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Chromogranin B.	0.490
CRHBP	COA7	ENSAMEP00000001924	ENSAMEP00000009868	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Cytochrome c oxidase assembly factor 7 (putative).	0.437
CRHBP	CRHR2	ENSAMEP00000001924	ENSAMEP00000007077	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.680
CRHBP	G1M7R8_AILME	ENSAMEP00000001924	ENSAMEP00000015388	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.721
CRHBP	HMGCR	ENSAMEP00000001924	ENSAMEP00000000725	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.490
CRHBP	KITLG	ENSAMEP00000001924	ENSAMEP00000002450	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.549
CRHBP	MNT	ENSAMEP00000001924	ENSAMEP00000007947	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	MAX network transcriptional repressor.	0.614
CRHBP	SLC17A3	ENSAMEP00000001924	ENSAMEP00000010410	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Solute carrier family 17 member 3.	0.568
CRHBP	UCN	ENSAMEP00000001924	ENSAMEP00000001698	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urocortin.	0.839
CRHR2	BDNF	ENSAMEP00000007077	ENSAMEP00000015321	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.427
CRHR2	CRHBP	ENSAMEP00000007077	ENSAMEP00000001924	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.680
CRHR2	G1M7R8_AILME	ENSAMEP00000007077	ENSAMEP00000015388	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.904

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