WDR4 protein (Ailuropoda melanoleuca) - STRING interaction network

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WDR4

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (406 aa)

Predicted Functional Partners:

METTL1

0.999

PUS1

0.917

TRMT61A

0.907

TRMT61B

0.879

TRMT6

0.820

FAM118A

0.802

PWP2

0.801

BOP1

0.795

DDX18

0.777

YRDC

0.766

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	DDX18	ENSAMEP00000006248	ENSAMEP00000013308	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.988
BOP1	METTL1	ENSAMEP00000006248	ENSAMEP00000005738	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	0.639
BOP1	PUS1	ENSAMEP00000006248	ENSAMEP00000014450	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pseudouridine synthase 1.	0.695
BOP1	PWP2	ENSAMEP00000006248	ENSAMEP00000011522	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.929
BOP1	TRMT6	ENSAMEP00000006248	ENSAMEP00000011206	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	tRNA methyltransferase 6.	0.690
BOP1	TRMT61A	ENSAMEP00000006248	ENSAMEP00000019189	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.	0.845
BOP1	TRMT61B	ENSAMEP00000006248	ENSAMEP00000005433	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	tRNA methyltransferase 61B.	0.728
BOP1	WDR4	ENSAMEP00000006248	ENSAMEP00000001938	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	0.795
DDX18	BOP1	ENSAMEP00000013308	ENSAMEP00000006248	RNA helicase.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.988
DDX18	METTL1	ENSAMEP00000013308	ENSAMEP00000005738	RNA helicase.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	0.529
DDX18	PUS1	ENSAMEP00000013308	ENSAMEP00000014450	RNA helicase.	Pseudouridine synthase 1.	0.764
DDX18	PWP2	ENSAMEP00000013308	ENSAMEP00000011522	RNA helicase.	Uncharacterized protein.	0.974
DDX18	TRMT6	ENSAMEP00000013308	ENSAMEP00000011206	RNA helicase.	tRNA methyltransferase 6.	0.789
DDX18	TRMT61A	ENSAMEP00000013308	ENSAMEP00000019189	RNA helicase.	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.	0.625
DDX18	WDR4	ENSAMEP00000013308	ENSAMEP00000001938	RNA helicase.	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	0.777
FAM118A	WDR4	ENSAMEP00000009502	ENSAMEP00000001938	Family with sequence similarity 118 member A.	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.	0.802
METTL1	BOP1	ENSAMEP00000005738	ENSAMEP00000006248	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.639
METTL1	DDX18	ENSAMEP00000005738	ENSAMEP00000013308	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	RNA helicase.	0.529
METTL1	PUS1	ENSAMEP00000005738	ENSAMEP00000014450	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	Pseudouridine synthase 1.	0.693
METTL1	PWP2	ENSAMEP00000005738	ENSAMEP00000011522	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	Uncharacterized protein.	0.407

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