Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR44WD repeat domain 44. (912 aa)    
Predicted Functional Partners:
VAPB
VAMP associated protein B and C.
   
 
 0.822
VAPA
VAMP associated protein A.
   
 
 0.702
OSBPL11
Oxysterol-binding protein; Belongs to the OSBP family.
    
 
 0.621
G1LBF0_AILME
Uncharacterized protein.
    
 
 0.620
KCTD7
Uncharacterized protein.
   
  
 0.603
LSM7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
   0.591
YIPF6
Protein YIPF.
   
  
 0.582
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
   
  
 0.565
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
   
  
 0.561
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
      
 0.560
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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