Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VPS45Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (572 aa)    
Predicted Functional Partners:
RBSN
Rabenosyn, RAB effector.
    
 0.993
STX16-NPEPL1
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
    
 
 0.963
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
   
 
 0.945
ERGIC3
ERGIC and golgi 3.
 
      0.899
VTI1B
Vesicle transport through interaction with t-SNAREs 1B.
   
 
 0.889
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
    
 0.889
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.887
RAB5A
RAB5A, member RAS oncogene family.
    
 0.876
COG4
Component of oligomeric golgi complex 4.
   
 
 0.874
G1L354_AILME
Syntaxin-6_N domain-containing protein.
    
 
 0.845
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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