Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADARB1Adenosine deaminase RNA specific B1. (718 aa)    
Predicted Functional Partners:
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.660
PRKRA
Protein activator of interferon induced protein kinase EIF2AK2.
    
 0.587
MECOM
MDS1 and EVI1 complex locus.
    
 
 0.535
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.510
STAU1
Double-stranded RNA-binding protein Staufen homolog 1; Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site (By similarity).
    
 0.501
LAMP5
Lysosomal associated membrane protein family member 5.
   
  
 0.499
ALYREF
Aly/REF export factor.
      
 0.489
ADAL
Adenosine deaminase like.
      
 0.459
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
 0.438
STRBP
Spermatid perinuclear RNA binding protein.
    
 
 0.421
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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