STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (540 aa)    
Predicted Functional Partners:
TMIE
Transmembrane inner ear.
      
 0.727
TPRN
Phostensin domain-containing protein.
      
 0.716
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.700
TMC1
Transmembrane channel-like protein.
    
 0.614
GIPC3
GIPC PDZ domain containing family member 3.
   
 
 0.564
CD109
CD109 molecule.
    
 0.549
SERPINA5
Serpin family A member 5; Belongs to the serpin family.
    
 0.543
GJB2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
  
 0.530
USH1C
USH1 protein network component harmonin.
      
 0.499
CEACAM1
Uncharacterized protein.
    
 0.493
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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