STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (385 aa)    
Predicted Functional Partners:
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.959
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.924
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.908
BCL2L1
BCL2 like 1.
     
 0.903
INS-IGF2
INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.880
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.863
EEA1
Early endosome antigen 1.
      
 0.853
LAMP2
Lysosomal associated membrane protein 2.
   
 
 0.830
ATP6AP2
ATPase H+ transporting accessory protein 2.
   
 0.826
CTSF
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.810
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.