STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD16Ankyrin repeat domain 16. (361 aa)    
Predicted Functional Partners:
NSMCE4A
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
    
 
 0.703
TMEM14C
Transmembrane protein 14C.
      
 0.640
CCDC12
Coiled-coil domain containing 12.
   
  
 0.618
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.612
RBM17
RNA binding motif protein 17.
    
 
 0.611
FBH1
F-box DNA helicase 1.
      
 0.604
PCMTD2
Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2.
    
 
 0.604
ARF5
ADP ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family.
   
 0.555
GDI2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
 
  
 0.538
LOC100471567
Olfactory receptor.
    
 0.537
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.