STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYT1Myelin transcription factor 1. (1118 aa)    
Predicted Functional Partners:
GAMT
Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
   
  
 0.541
FLI1
Fli-1 proto-oncogene, ETS transcription factor.
   
  
 0.528
ZNF35
Zinc finger protein 35.
      
 0.528
WEE1
WEE1 G2 checkpoint kinase.
      
 0.512
NFX1
Nuclear transcription factor, X-box binding 1.
      
 0.482
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 
 0.459
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.459
HDAC2
Histone deacetylase 2.
    
 
 0.459
PJA2
Praja ring finger ubiquitin ligase 2.
      
 0.456
G1L8Y5_AILME
Uncharacterized protein.
   
   0.414
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.