MECOM protein (Ailuropoda melanoleuca) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

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Score

MECOM

MDS1 and EVI1 complex locus. (1116 aa)

Predicted Functional Partners:

CTBP2

0.935

CTBP1

0.935

HDAC1

0.920

HDAC2

0.920

MAPK10

0.904

MAPK8

0.904

MAPK9

0.902

G1MM36_AILME

0.761

RBBP7

0.742

G1LA80_AILME

0.676

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP1	CTBP2	ENSAMEP00000017830	ENSAMEP00000004373	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.933
CTBP1	HDAC1	ENSAMEP00000017830	ENSAMEP00000008076	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.938
CTBP1	HDAC2	ENSAMEP00000017830	ENSAMEP00000013919	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2.	0.938
CTBP1	MECOM	ENSAMEP00000017830	ENSAMEP00000002205	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	MDS1 and EVI1 complex locus.	0.935
CTBP2	CTBP1	ENSAMEP00000004373	ENSAMEP00000017830	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.933
CTBP2	HDAC1	ENSAMEP00000004373	ENSAMEP00000008076	C-terminal binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.913
CTBP2	HDAC2	ENSAMEP00000004373	ENSAMEP00000013919	C-terminal binding protein 2.	Histone deacetylase 2.	0.913
CTBP2	MECOM	ENSAMEP00000004373	ENSAMEP00000002205	C-terminal binding protein 2.	MDS1 and EVI1 complex locus.	0.935
G1LA80_AILME	HDAC1	ENSAMEP00000003803	ENSAMEP00000008076	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.808
G1LA80_AILME	HDAC2	ENSAMEP00000003803	ENSAMEP00000013919	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase 2.	0.808
G1LA80_AILME	MECOM	ENSAMEP00000003803	ENSAMEP00000002205	WD_REPEATS_REGION domain-containing protein.	MDS1 and EVI1 complex locus.	0.676
G1LA80_AILME	RBBP7	ENSAMEP00000003803	ENSAMEP00000010776	WD_REPEATS_REGION domain-containing protein.	RB binding protein 7, chromatin remodeling factor.	0.909
G1MM36_AILME	MECOM	ENSAMEP00000020425	ENSAMEP00000002205	Uncharacterized protein.	MDS1 and EVI1 complex locus.	0.761
HDAC1	CTBP1	ENSAMEP00000008076	ENSAMEP00000017830	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.938
HDAC1	CTBP2	ENSAMEP00000008076	ENSAMEP00000004373	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	C-terminal binding protein 2.	0.913
HDAC1	G1LA80_AILME	ENSAMEP00000008076	ENSAMEP00000003803	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	WD_REPEATS_REGION domain-containing protein.	0.808
HDAC1	HDAC2	ENSAMEP00000008076	ENSAMEP00000013919	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.993
HDAC1	MECOM	ENSAMEP00000008076	ENSAMEP00000002205	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	MDS1 and EVI1 complex locus.	0.920
HDAC1	RBBP7	ENSAMEP00000008076	ENSAMEP00000010776	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RB binding protein 7, chromatin remodeling factor.	0.890
HDAC2	CTBP1	ENSAMEP00000013919	ENSAMEP00000017830	Histone deacetylase 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.938