IGF2 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

IGF2

Insulin like growth factor 2. (238 aa)

Predicted Functional Partners:

IGF2R

0.999

IGF1R

0.968

IGFBP6

0.963

IGFBP3

0.953

IGF1

0.951

G1M8B3_AILME

0.947

IGFBP2

0.946

GPC3

0.945

INSR

0.936

IGFBP5

0.880

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1M8B3_AILME	IGF1	ENSAMEP00000015583	ENSAMEP00000006724	Uncharacterized protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.949
G1M8B3_AILME	IGF2	ENSAMEP00000015583	ENSAMEP00000002277	Uncharacterized protein.	Insulin like growth factor 2.	0.947
G1M8B3_AILME	IGF2R	ENSAMEP00000015583	ENSAMEP00000016198	Uncharacterized protein.	Insulin like growth factor 2 receptor.	0.552
G1M8B3_AILME	IGFBP3	ENSAMEP00000015583	ENSAMEP00000015567	Uncharacterized protein.	Thyroglobulin type-1 domain-containing protein.	0.761
G1M8B3_AILME	IGFBP6	ENSAMEP00000015583	ENSAMEP00000012773	Uncharacterized protein.	Insulin like growth factor binding protein 6.	0.728
GPC3	IGF2	ENSAMEP00000001496	ENSAMEP00000002277	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Insulin like growth factor 2.	0.945
IGF1	G1M8B3_AILME	ENSAMEP00000006724	ENSAMEP00000015583	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Uncharacterized protein.	0.949
IGF1	IGF1R	ENSAMEP00000006724	ENSAMEP00000006007	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Tyrosine-protein kinase receptor.	0.962
IGF1	IGF2	ENSAMEP00000006724	ENSAMEP00000002277	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor 2.	0.951
IGF1	IGF2R	ENSAMEP00000006724	ENSAMEP00000016198	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor 2 receptor.	0.700
IGF1	IGFBP2	ENSAMEP00000006724	ENSAMEP00000003547	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 2.	0.914
IGF1	IGFBP3	ENSAMEP00000006724	ENSAMEP00000015567	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Thyroglobulin type-1 domain-containing protein.	0.990
IGF1	IGFBP5	ENSAMEP00000006724	ENSAMEP00000003543	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 5.	0.918
IGF1	IGFBP6	ENSAMEP00000006724	ENSAMEP00000012773	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 6.	0.933
IGF1	INSR	ENSAMEP00000006724	ENSAMEP00000008683	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Tyrosine-protein kinase receptor.	0.987
IGF1R	IGF1	ENSAMEP00000006007	ENSAMEP00000006724	Tyrosine-protein kinase receptor.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.962
IGF1R	IGF2	ENSAMEP00000006007	ENSAMEP00000002277	Tyrosine-protein kinase receptor.	Insulin like growth factor 2.	0.968
IGF1R	INSR	ENSAMEP00000006007	ENSAMEP00000008683	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.901
IGF2	G1M8B3_AILME	ENSAMEP00000002277	ENSAMEP00000015583	Insulin like growth factor 2.	Uncharacterized protein.	0.947
IGF2	GPC3	ENSAMEP00000002277	ENSAMEP00000001496	Insulin like growth factor 2.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.945