TEAD1 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TEAD1

TEA domain transcription factor 1. (384 aa)

Predicted Functional Partners:

YAP1

0.997

WWTR1

0.977

TEAD2

0.901

LEF1

0.817

TCF7L1

0.809

VGLL4

0.796

LATS1

0.638

CIZ1

0.582

LATS2

0.557

RUNX2

0.549

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIZ1	TEAD1	ENSAMEP00000016127	ENSAMEP00000002402	CDKN1A interacting zinc finger protein 1.	TEA domain transcription factor 1.	0.582
LATS1	LATS2	ENSAMEP00000019311	ENSAMEP00000015456	Large tumor suppressor kinase 1.	Large tumor suppressor kinase 2.	0.974
LATS1	TEAD1	ENSAMEP00000019311	ENSAMEP00000002402	Large tumor suppressor kinase 1.	TEA domain transcription factor 1.	0.638
LATS1	VGLL4	ENSAMEP00000019311	ENSAMEP00000011580	Large tumor suppressor kinase 1.	Vestigial like family member 4.	0.510
LATS1	WWTR1	ENSAMEP00000019311	ENSAMEP00000010941	Large tumor suppressor kinase 1.	WW domain containing transcription regulator 1.	0.986
LATS1	YAP1	ENSAMEP00000019311	ENSAMEP00000010528	Large tumor suppressor kinase 1.	Yes associated protein 1.	0.993
LATS2	LATS1	ENSAMEP00000015456	ENSAMEP00000019311	Large tumor suppressor kinase 2.	Large tumor suppressor kinase 1.	0.974
LATS2	TEAD1	ENSAMEP00000015456	ENSAMEP00000002402	Large tumor suppressor kinase 2.	TEA domain transcription factor 1.	0.557
LATS2	WWTR1	ENSAMEP00000015456	ENSAMEP00000010941	Large tumor suppressor kinase 2.	WW domain containing transcription regulator 1.	0.986
LATS2	YAP1	ENSAMEP00000015456	ENSAMEP00000010528	Large tumor suppressor kinase 2.	Yes associated protein 1.	0.993
LEF1	RUNX2	ENSAMEP00000001900	ENSAMEP00000009709	Lymphoid enhancer binding factor 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.730
LEF1	TCF7L1	ENSAMEP00000001900	ENSAMEP00000002181	Lymphoid enhancer binding factor 1.	Transcription factor 7 like 1.	0.953
LEF1	TEAD1	ENSAMEP00000001900	ENSAMEP00000002402	Lymphoid enhancer binding factor 1.	TEA domain transcription factor 1.	0.817
LEF1	TEAD2	ENSAMEP00000001900	ENSAMEP00000014974	Lymphoid enhancer binding factor 1.	TEA domain transcription factor 2.	0.804
LEF1	YAP1	ENSAMEP00000001900	ENSAMEP00000010528	Lymphoid enhancer binding factor 1.	Yes associated protein 1.	0.837
RUNX2	LEF1	ENSAMEP00000009709	ENSAMEP00000001900	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Lymphoid enhancer binding factor 1.	0.730
RUNX2	TCF7L1	ENSAMEP00000009709	ENSAMEP00000002181	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Transcription factor 7 like 1.	0.414
RUNX2	TEAD1	ENSAMEP00000009709	ENSAMEP00000002402	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	TEA domain transcription factor 1.	0.549
RUNX2	WWTR1	ENSAMEP00000009709	ENSAMEP00000010941	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	WW domain containing transcription regulator 1.	0.635
RUNX2	YAP1	ENSAMEP00000009709	ENSAMEP00000010528	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Yes associated protein 1.	0.603