Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G1L6B0_AILMEPOU-specific domain-containing protein. (307 aa)    
Predicted Functional Partners:
G1LIM1_AILME
Homeobox domain-containing protein.
   
 0.905
NANOG
Homeobox domain-containing protein.
   
 0.905
SOX2
SRY-box transcription factor 2.
    
 0.876
G1L646_AILME
Uncharacterized protein.
   
 0.866
SALL4
Uncharacterized protein.
   
 0.866
CTNNB1
Catenin beta 1.
    
 0.810
CHD4
Uncharacterized protein.
    
 
 0.809
SOX15
SRY-box transcription factor 15.
    
 0.808
ARID3B
AT-rich interaction domain 3B.
   
 
 0.805
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 
 0.805
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (16%) [HD]