MOV10L1 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MOV10L1

Mov10 like RISC complex RNA helicase 1. (1150 aa)

Predicted Functional Partners:

TDRD5

0.638

ASZ1

0.607

PNLDC1

0.574

PIWIL2

0.568

TDRKH

0.565

DDX10

0.551

DDX17

0.542

AGO2

0.536

FMR1

0.532

G1LQP8_AILME

0.530

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	DDX17	ENSAMEP00000005384	ENSAMEP00000011163	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.503
AGO2	FMR1	ENSAMEP00000005384	ENSAMEP00000015852	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Fragile X mental retardation 1.	0.704
AGO2	MOV10L1	ENSAMEP00000005384	ENSAMEP00000002439	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Mov10 like RISC complex RNA helicase 1.	0.536
ASZ1	G1LQP8_AILME	ENSAMEP00000001309	ENSAMEP00000009382	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Uncharacterized protein; Belongs to the argonaute family.	0.472
ASZ1	MOV10L1	ENSAMEP00000001309	ENSAMEP00000002439	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Mov10 like RISC complex RNA helicase 1.	0.607
ASZ1	PIWIL2	ENSAMEP00000001309	ENSAMEP00000003382	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.	0.699
ASZ1	TDRD5	ENSAMEP00000001309	ENSAMEP00000015531	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.	0.461
ASZ1	TDRKH	ENSAMEP00000001309	ENSAMEP00000000498	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor and KH domain containing.	0.605
DDX10	DDX17	ENSAMEP00000009740	ENSAMEP00000011163	RNA helicase.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.532
DDX10	MOV10L1	ENSAMEP00000009740	ENSAMEP00000002439	RNA helicase.	Mov10 like RISC complex RNA helicase 1.	0.551
DDX17	AGO2	ENSAMEP00000011163	ENSAMEP00000005384	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.503
DDX17	DDX10	ENSAMEP00000011163	ENSAMEP00000009740	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	RNA helicase.	0.532
DDX17	MOV10L1	ENSAMEP00000011163	ENSAMEP00000002439	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Mov10 like RISC complex RNA helicase 1.	0.542
FMR1	AGO2	ENSAMEP00000015852	ENSAMEP00000005384	Fragile X mental retardation 1.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.704
FMR1	MOV10L1	ENSAMEP00000015852	ENSAMEP00000002439	Fragile X mental retardation 1.	Mov10 like RISC complex RNA helicase 1.	0.532
G1LQP8_AILME	ASZ1	ENSAMEP00000009382	ENSAMEP00000001309	Uncharacterized protein; Belongs to the argonaute family.	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	0.472
G1LQP8_AILME	MOV10L1	ENSAMEP00000009382	ENSAMEP00000002439	Uncharacterized protein; Belongs to the argonaute family.	Mov10 like RISC complex RNA helicase 1.	0.530
G1LQP8_AILME	TDRD5	ENSAMEP00000009382	ENSAMEP00000015531	Uncharacterized protein; Belongs to the argonaute family.	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.	0.531
G1LQP8_AILME	TDRKH	ENSAMEP00000009382	ENSAMEP00000000498	Uncharacterized protein; Belongs to the argonaute family.	Tudor and KH domain containing.	0.667
MOV10L1	AGO2	ENSAMEP00000002439	ENSAMEP00000005384	Mov10 like RISC complex RNA helicase 1.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.536