STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP1E3 ubiquitin-protein ligase. (920 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
   
  0.987
KLF5
Kruppel like factor 5.
    
 0.952
SMURF1
E3 ubiquitin-protein ligase.
    
  0.918
SMURF2
E3 ubiquitin-protein ligase.
    
 0.913
FGFR3
Fibroblast growth factor receptor.
    
  0.910
FGFR4
Fibroblast growth factor receptor.
    
  0.910
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
  0.907
ARRDC1
Arrestin domain containing 1.
    
 
 0.896
SMAD7
Mothers against decapentaplegic homolog.
    
 0.893
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.889
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.