STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21SPG21 abhydrolase domain containing, maspardin. (308 aa)    
Predicted Functional Partners:
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.755
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.751
CD58
Uncharacterized protein.
      
 0.749
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.737
LTF
Lactotransferrin; Belongs to the transferrin family.
      
 0.664
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
      
 0.603
PAAF1
Proteasomal ATPase associated factor 1.
      
 0.603
NIPA1
NIPA magnesium transporter 1.
      
 0.591
TECPR2
Tectonin beta-propeller repeat containing 2.
      
 0.545
ZNF862
Zinc finger protein 862.
      
 0.528
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.