STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (855 aa)    
Predicted Functional Partners:
PAK1
Non-specific serine/threonine protein kinase.
    
 0.964
PAK3
P21 (RAC1) activated kinase 3.
    
 0.938
GIT2
GIT ArfGAP 2.
    
 0.848
GIT1
GIT ArfGAP 1.
    
 0.832
PAK2
Non-specific serine/threonine protein kinase.
    
 0.786
ARHGEF19
Rho guanine nucleotide exchange factor 19.
     
 0.779
ITSN2
Intersectin 2.
   
 
0.755
G1LH72_AILME
Uncharacterized protein.
   
 0.751
CDC42
Cell division cycle 42.
   
 0.751
ARHGEF10
Rho guanine nucleotide exchange factor 10.
   
 
0.730
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.