STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ME2Malic enzyme. (584 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.981
FH
Fumarate hydratase.
  
 
 0.981
MDH1
Malate dehydrogenase.
  
 0.956
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.953
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.952
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.948
MDH2
Malate dehydrogenase.
  
 0.946
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.934
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.934
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.934
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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