FOCAD protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

FOCAD

Focadhesin. (1805 aa)

Predicted Functional Partners:

AVEN

0.874

HACD4

0.680

PCDHAC2

0.499

G1LCH4_AILME

0.489

ANAPC15

0.484

PRICKLE1

0.461

GIGYF1

0.446

TMEM209

0.438

EXOSC5

0.421

VSIG10

0.421

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC15	FOCAD	ENSAMEP00000011393	ENSAMEP00000003166	Anaphase promoting complex subunit 15.	Focadhesin.	0.484
ANAPC15	TMEM209	ENSAMEP00000011393	ENSAMEP00000005795	Anaphase promoting complex subunit 15.	Transmembrane protein 209.	0.470
AVEN	FOCAD	ENSAMEP00000016629	ENSAMEP00000003166	Uncharacterized protein.	Focadhesin.	0.874
EXOSC5	FOCAD	ENSAMEP00000012234	ENSAMEP00000003166	Exosome component 5.	Focadhesin.	0.421
EXOSC5	HACD4	ENSAMEP00000012234	ENSAMEP00000003175	Exosome component 5.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.417
FOCAD	ANAPC15	ENSAMEP00000003166	ENSAMEP00000011393	Focadhesin.	Anaphase promoting complex subunit 15.	0.484
FOCAD	AVEN	ENSAMEP00000003166	ENSAMEP00000016629	Focadhesin.	Uncharacterized protein.	0.874
FOCAD	EXOSC5	ENSAMEP00000003166	ENSAMEP00000012234	Focadhesin.	Exosome component 5.	0.421
FOCAD	G1LCH4_AILME	ENSAMEP00000003166	ENSAMEP00000004603	Focadhesin.	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.489
FOCAD	GIGYF1	ENSAMEP00000003166	ENSAMEP00000015542	Focadhesin.	GRB10 interacting GYF protein 1.	0.446
FOCAD	HACD4	ENSAMEP00000003166	ENSAMEP00000003175	Focadhesin.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.680
FOCAD	PCDHAC2	ENSAMEP00000003166	ENSAMEP00000011304	Focadhesin.	Protocadherin alpha subfamily C, 2.	0.499
FOCAD	PRICKLE1	ENSAMEP00000003166	ENSAMEP00000014561	Focadhesin.	Prickle planar cell polarity protein 1.	0.461
FOCAD	TMEM209	ENSAMEP00000003166	ENSAMEP00000005795	Focadhesin.	Transmembrane protein 209.	0.438
FOCAD	VSIG10	ENSAMEP00000003166	ENSAMEP00000017041	Focadhesin.	V-set and immunoglobulin domain containing 10.	0.421
G1LCH4_AILME	FOCAD	ENSAMEP00000004603	ENSAMEP00000003166	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	Focadhesin.	0.489
G1LCH4_AILME	VSIG10	ENSAMEP00000004603	ENSAMEP00000017041	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	V-set and immunoglobulin domain containing 10.	0.459
GIGYF1	FOCAD	ENSAMEP00000015542	ENSAMEP00000003166	GRB10 interacting GYF protein 1.	Focadhesin.	0.446
HACD4	EXOSC5	ENSAMEP00000003175	ENSAMEP00000012234	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Exosome component 5.	0.417
HACD4	FOCAD	ENSAMEP00000003175	ENSAMEP00000003166	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Focadhesin.	0.680