STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity); Belongs to the somatotropin/prolactin family. (216 aa)    
Predicted Functional Partners:
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
   
0.994
GHR
Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity).
    
 0.989
GHRH
Growth hormone releasing hormone.
   
  
 0.981
GHRL
Uncharacterized protein.
   
 
 0.966
AMELX
Amelogenin X-linked.
   
    0.960
PRPH2
Peripherin 2.
   
    0.960
BPIFA2
BPI1 domain-containing protein.
   
    0.960
LOC100479155
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
   
    0.960
LOC100464577
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
    0.958
NPY2R
Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family.
   
    0.958
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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