STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (1018 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.982
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.814
DDX58
DExD/H-box helicase 58.
   
 
 0.794
PENK
Proenkephalin.
      
 0.749
OASL
Uncharacterized protein.
   
 0.741
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.729
G1MP54_AILME
Uncharacterized protein.
   
 
 0.722
G1MP55_AILME
Uncharacterized protein.
   
 
 0.722
BPIFA1
BPI fold containing family A member 1.
    
 
 0.713
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.699
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.