PDE1A protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

PDE1A

Phosphodiesterase. (503 aa)

Predicted Functional Partners:

CALML5

0.943

CALML6

0.940

CALML4

0.933

GNAT3

0.929

ADCY8

0.921

PDE1B

0.920

ENTPD3

0.915

APRT

0.913

ENPP3

0.913

ENPP1

0.913

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY8	CALML4	ENSAMEP00000013773	ENSAMEP00000014809	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 4.	0.949
ADCY8	CALML5	ENSAMEP00000013773	ENSAMEP00000020510	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 5.	0.942
ADCY8	CALML6	ENSAMEP00000013773	ENSAMEP00000014297	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 6.	0.948
ADCY8	ENPP1	ENSAMEP00000013773	ENSAMEP00000011068	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.904
ADCY8	ENPP3	ENSAMEP00000013773	ENSAMEP00000011003	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.836
ADCY8	ENTPD3	ENSAMEP00000013773	ENSAMEP00000001779	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.850
ADCY8	GNAT3	ENSAMEP00000013773	ENSAMEP00000017122	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha transducin 3.	0.604
ADCY8	PDE1A	ENSAMEP00000013773	ENSAMEP00000003296	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Phosphodiesterase.	0.921
ADCY8	PDE1B	ENSAMEP00000013773	ENSAMEP00000001139	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Phosphodiesterase.	0.921
APRT	ENPP1	ENSAMEP00000000381	ENSAMEP00000011068	Adenine phosphoribosyltransferase.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.908
APRT	ENPP3	ENSAMEP00000000381	ENSAMEP00000011003	Adenine phosphoribosyltransferase.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.908
APRT	ENTPD3	ENSAMEP00000000381	ENSAMEP00000001779	Adenine phosphoribosyltransferase.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.912
APRT	PDE1A	ENSAMEP00000000381	ENSAMEP00000003296	Adenine phosphoribosyltransferase.	Phosphodiesterase.	0.913
APRT	PDE1B	ENSAMEP00000000381	ENSAMEP00000001139	Adenine phosphoribosyltransferase.	Phosphodiesterase.	0.920
CALML4	ADCY8	ENSAMEP00000014809	ENSAMEP00000013773	Calmodulin like 4.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.949
CALML4	CALML5	ENSAMEP00000014809	ENSAMEP00000020510	Calmodulin like 4.	Calmodulin like 5.	0.932
CALML4	CALML6	ENSAMEP00000014809	ENSAMEP00000014297	Calmodulin like 4.	Calmodulin like 6.	0.934
CALML4	PDE1A	ENSAMEP00000014809	ENSAMEP00000003296	Calmodulin like 4.	Phosphodiesterase.	0.933
CALML4	PDE1B	ENSAMEP00000014809	ENSAMEP00000001139	Calmodulin like 4.	Phosphodiesterase.	0.881
CALML5	ADCY8	ENSAMEP00000020510	ENSAMEP00000013773	Calmodulin like 5.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.942